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Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial

Received: 29 January 2021     Accepted: 6 February 2021     Published: 27 February 2021
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Abstract

Wound healing complications (WHCs) in the groin after vascular surgeries are a serious problem for patients and surgeons in various surgical disciplines. The incidence of WHCs of up to 44% after incisions in the groin is often responsible for prolonged hospital stay and high treatment costs. An effective reduction of WHCs for various wound types after using closed incision negative pressure therapy (ciNPT) has been documented in many case reports and clinical studies. As the majority of studies have addressed the effect of ciNPT on primary groin incision wounds, concerning groin incision wounds after revision vascular surgery are extremely scarce. The aim of this prospective, randomized clinical study was to investigate the effectiveness of ciNPT compared with conventional therapy on groin incisions after revision vascular surgery. We analyzed the cases of a total of 94 patients with 100 groin incisions. Patients were randomized and treated with either PREVENA™ (n=47 groins) or a conventional adhesive dressing (n=53 groins; control group). PREVENA™ was applied intraoperatively and was removed on day 5, 6 or 7 postoperatively. Wound evaluation was carried out on the 5th to 7th and 30th postoperative day. Compared with the control group, the ciNPT group showed a reduction in the overall incidence of WHCs assessed 30 days postoperatively (p<0.0005). With regard to prevention of revision surgeries, the ciNPT had no significant impact (p=0.056). Subgroup analysis revealed a significant effect of ciNPT for almost all wound healing risk factors. Based on our results, ciNPT provides a promising therapeutic option to reduce the frequency of postoperative WHCs and the need for revision surgeries in the groin after revision vascular surgery in patients with wound healing risk factors.

Published in Journal of Surgery (Volume 9, Issue 1)
DOI 10.11648/j.js.20210901.17
Page(s) 36-44
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Closed Incision Negative Pressure Therapy, Surgical Site Infections, Postoperative Wound Complications, Wound Healing

References
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Cite This Article
  • APA Style

    Sebastian Paul Pleger, Liesa Fuhrmann, Mouiad Al Tattan, Alexander Kunold, Meshal Elzien, et al. (2021). Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial. Journal of Surgery, 9(1), 36-44. https://doi.org/10.11648/j.js.20210901.17

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    ACS Style

    Sebastian Paul Pleger; Liesa Fuhrmann; Mouiad Al Tattan; Alexander Kunold; Meshal Elzien, et al. Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial. J. Surg. 2021, 9(1), 36-44. doi: 10.11648/j.js.20210901.17

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    AMA Style

    Sebastian Paul Pleger, Liesa Fuhrmann, Mouiad Al Tattan, Alexander Kunold, Meshal Elzien, et al. Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial. J Surg. 2021;9(1):36-44. doi: 10.11648/j.js.20210901.17

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  • @article{10.11648/j.js.20210901.17,
      author = {Sebastian Paul Pleger and Liesa Fuhrmann and Mouiad Al Tattan and Alexander Kunold and Meshal Elzien and Andreas Böning and Ahmed Koshty},
      title = {Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial},
      journal = {Journal of Surgery},
      volume = {9},
      number = {1},
      pages = {36-44},
      doi = {10.11648/j.js.20210901.17},
      url = {https://doi.org/10.11648/j.js.20210901.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20210901.17},
      abstract = {Wound healing complications (WHCs) in the groin after vascular surgeries are a serious problem for patients and surgeons in various surgical disciplines. The incidence of WHCs of up to 44% after incisions in the groin is often responsible for prolonged hospital stay and high treatment costs. An effective reduction of WHCs for various wound types after using closed incision negative pressure therapy (ciNPT) has been documented in many case reports and clinical studies. As the majority of studies have addressed the effect of ciNPT on primary groin incision wounds, concerning groin incision wounds after revision vascular surgery are extremely scarce. The aim of this prospective, randomized clinical study was to investigate the effectiveness of ciNPT compared with conventional therapy on groin incisions after revision vascular surgery. We analyzed the cases of a total of 94 patients with 100 groin incisions. Patients were randomized and treated with either PREVENA™ (n=47 groins) or a conventional adhesive dressing (n=53 groins; control group). PREVENA™ was applied intraoperatively and was removed on day 5, 6 or 7 postoperatively. Wound evaluation was carried out on the 5th to 7th and 30th postoperative day. Compared with the control group, the ciNPT group showed a reduction in the overall incidence of WHCs assessed 30 days postoperatively (p<0.0005). With regard to prevention of revision surgeries, the ciNPT had no significant impact (p=0.056). Subgroup analysis revealed a significant effect of ciNPT for almost all wound healing risk factors. Based on our results, ciNPT provides a promising therapeutic option to reduce the frequency of postoperative WHCs and the need for revision surgeries in the groin after revision vascular surgery in patients with wound healing risk factors.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Closed Incision Negative Pressure Therapy for Management of Incision Wounds in the Groin After Revision Vascular Surgery: A Randomized Controlled Trial
    AU  - Sebastian Paul Pleger
    AU  - Liesa Fuhrmann
    AU  - Mouiad Al Tattan
    AU  - Alexander Kunold
    AU  - Meshal Elzien
    AU  - Andreas Böning
    AU  - Ahmed Koshty
    Y1  - 2021/02/27
    PY  - 2021
    N1  - https://doi.org/10.11648/j.js.20210901.17
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    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 36
    EP  - 44
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20210901.17
    AB  - Wound healing complications (WHCs) in the groin after vascular surgeries are a serious problem for patients and surgeons in various surgical disciplines. The incidence of WHCs of up to 44% after incisions in the groin is often responsible for prolonged hospital stay and high treatment costs. An effective reduction of WHCs for various wound types after using closed incision negative pressure therapy (ciNPT) has been documented in many case reports and clinical studies. As the majority of studies have addressed the effect of ciNPT on primary groin incision wounds, concerning groin incision wounds after revision vascular surgery are extremely scarce. The aim of this prospective, randomized clinical study was to investigate the effectiveness of ciNPT compared with conventional therapy on groin incisions after revision vascular surgery. We analyzed the cases of a total of 94 patients with 100 groin incisions. Patients were randomized and treated with either PREVENA™ (n=47 groins) or a conventional adhesive dressing (n=53 groins; control group). PREVENA™ was applied intraoperatively and was removed on day 5, 6 or 7 postoperatively. Wound evaluation was carried out on the 5th to 7th and 30th postoperative day. Compared with the control group, the ciNPT group showed a reduction in the overall incidence of WHCs assessed 30 days postoperatively (p<0.0005). With regard to prevention of revision surgeries, the ciNPT had no significant impact (p=0.056). Subgroup analysis revealed a significant effect of ciNPT for almost all wound healing risk factors. Based on our results, ciNPT provides a promising therapeutic option to reduce the frequency of postoperative WHCs and the need for revision surgeries in the groin after revision vascular surgery in patients with wound healing risk factors.
    VL  - 9
    IS  - 1
    ER  - 

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Author Information
  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

  • Department of Vascular Surgery, Jung-Stilling Hospital, Siegen, Germany

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